Detaillierte Hinweise zur Methadontabletten zur Schmerzbehandlung
Detaillierte Hinweise zur Methadontabletten zur Schmerzbehandlung
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Because of the potential for serious adverse reactions in nursing infants from methadone, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Regardless of the dose determination strategy employed, methadone is most safely initiated and titrated using small initial doses and gradual dose adjustments.
If you take too much methadone hydrochloride tablets or overdose, call 911 or your local emergency number right away.
Selection of patients for treatment with methadone should be governed by the same principles that apply to the use of other opioids (Weiher INDICATIONS AND USAGE).
The total daily dose, potency and specific characteristics of the opioid the patient had been taking previously, if any;
If you become pregnant while taking this drug, call your doctor right away. Children World health organization are born to mothers Weltgesundheitsorganisation used this drug for a long time during pregnancy are at risk of neonatal withdrawal syndrome. This can Beryllium life threatening to the child.
Additional information on the potential risks of methadone may Beryllium derived from animal data. Methadone does not appear to be teratogenic hinein the rat or rabbit models. However, following large doses, methadone produced teratogenic effects in the guinea pig, hamster and maus. One published study in pregnant hamsters indicated that a single subcutaneous dose of methadone ranging from 31 to 185 mg/kg (the 31 mg/kg dose is approximately 2 times a human daily oral dose of 120 mg/day on a mg/m2 Stützpunkt) on day 8 of gestation resulted in a decrease in the number of fetuses mit hilfe litter and an increase in the percentage of fetuses exhibiting congenital malformations described as exencephaly, cranioschisis, and “various other lesions”.
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For seniors: The kidneys of older adults may not Methadontabletten 10 mg online work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays hinein your body for a longer time. This raises your risk of side effects.
These can be symptoms that you have taken too much (overdose of) methadone hydrochloride tablets, or the dose is too high for you. They can also Beryllium symptoms of a serious heart reaction. These symptoms can lead to serious problems or death if not treated right away.
Rein these patients, even usual therapeutic doses of methadone may decrease respiratory drive while simultaneously increasing airway resistance to the point of apnea. Alternative, non-opioid analgesics should Beryllium considered, and methadone should Beryllium used at the lowest effective dose and only under careful medical supervision.
For people with seizures: This drug may cause more seizures in people with epilepsy. If your seizure control gets worse while taking this drug, call your doctor.
Examples of benzodiazepines include lorazepam, clonazepam, and alprazolam. These drugs should only Beryllium used with methadone when other drugs don’t work well enough.
For children: The safety and effectiveness of this drug haven’t been established hinein children. It shouldn’t be used in children younger than 18 years. Children who accidentally take this drug have a high risk of death from overdosing.